CHTF18

CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
Identifiers
Symbols CHTF18; C16orf41; C321D2.2; C321D2.3; C321D2.4; CHL12; Ctf18; RUVBL
External IDs OMIM613201 MGI2384887 HomoloGene32532 GeneCards: CHTF18 Gene
Orthologs
Species Human Mouse
Entrez 63922 214901
Ensembl ENSG00000127586 ENSMUSG00000019214
UniProt Q8WVB6 n/a
RefSeq (mRNA) NM_022092 NM_145409.2
RefSeq (protein) NP_071375 NP_663384.2
Location (UCSC) Chr 16:
0.84 – 0.85 Mb
Chr 17:
25.86 – 25.86 Mb
PubMed search [1] [2]

Chromosome transmission fidelity protein 18 homolog is a protein that in humans is encoded by the CHTF18 gene.[1][2]

Interactions

CHTF18 has been shown to interact with DCC1,[3][4] RFC2,[3][4] RFC3,[3][4] PCNA,[1] RFC4[3] and RFC5.[3]

References

  1. ^ a b Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T (Oct 2002). "A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". J Biol Chem 277 (43): 40362–7. doi:10.1074/jbc.M206194200. PMID 12171929. 
  2. ^ "Entrez Gene: CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63922. 
  3. ^ a b c d e Bermudez, Vladimir P; Maniwa Yoshimasa, Tappin Inger, Ozato Keiko, Yokomori Kyoko, Hurwitz Jerard (Sep. 2003). "The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA". Proc. Natl. Acad. Sci. U.S.A. (United States) 100 (18): 10237–42. doi:10.1073/pnas.1434308100. ISSN 0027-8424. PMC 193545. PMID 12930902. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=193545. 
  4. ^ a b c Merkle, Carolin J; Karnitz Larry M, Henry-Sánchez John T, Chen Junjie (Aug. 2003). "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment". J. Biol. Chem. (United States) 278 (32): 30051–6. doi:10.1074/jbc.M211591200. ISSN 0021-9258. PMID 12766176. 

Further reading