CFU-GM
| CFU-GM |
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| Lineage. Captions in Polish, but "GMP" visible near bottom center. |
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TH H2.00.04.3.02009 |
CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit. It is derived from CFU-GEMM.
The "GM" stands for "granulocyte, monocyte".[1]
It is the precursor for monoblasts and myeloblasts.
Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).
Granulocytes
There is some controversy over which granulocytes derive from CFU-GM.
- There is little disagreement that neutrophils come from CFU-GM.
- Other sources state that basophils do not derive from CFU-GM, but from a distinct CFU, titled "CFU-Baso".[3]
See also
References
External links
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Cellular/
HSCs |
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cell/phys (coag, heme, immu, gran), csfs
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rbmg/mogr/tumr/hist, sysi/epon, btst
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drug (B1/2/3+5+6), btst, trns
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| Hematopoiesis |
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| Hemostasis |
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| Other |
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cell/phys (coag, heme, immu, gran), csfs
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rbmg/mogr/tumr/hist, sysi/epon, btst
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drug (B1/2/3+5+6), btst, trns
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