CENTG3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

Identifiers

AGAP3; CENTG3; CRAG; FLJ16146; FLJ34452; MRIP-1

External IDs

MGI: 2183446 HomoloGene: 23742 GeneCards: AGAP3 Gene

Gene Ontology
Molecular function	• nucleotide binding • GTP binding • ARF GTPase activator activity • zinc ion binding • metal ion binding
Cellular component	• intracellular • cytoplasm • membrane
Biological process	• signal transduction • small GTPase mediated signal transduction • regulation of ARF GTPase activity
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000133612

ENSMUSG00000023353

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 7:
150.78 – 150.84 Mb

Chr 5:
23.96 – 24.01 Mb

PubMed search

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene.^[1]

References

^ "Entrez Gene: CENTG3 centaurin, gamma 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=116988.

Further reading

Beausoleil SA, Villén J, Gerber SA et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–1292. doi:10.1038/nbt1240. PMID 16964243.
Qin Q, Inatome R, Hotta A et al. (2006). "A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein". J. Cell Biol. 172 (4): 497–504. doi:10.1083/jcb.200505079. PMC 2063670. PMID 16461359. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2063670.
Meurer S, Pioch S, Wagner K et al. (2005). "AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase". J. Biol. Chem. 279 (47): 49346–49354. doi:10.1074/jbc.M410565200. PMID 15381706.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Surks HK, Richards CT, Mendelsohn ME (2004). "Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA". J. Biol. Chem. 278 (51): 51484–51493. doi:10.1074/jbc.M305622200. PMID 14506264.
Scherer SW, Cheung J, MacDonald JR et al. (2003). "Human chromosome 7: DNA sequence and biology". Science 300 (5620): 767–772. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2882961.
Xia C, Ma W, Stafford LJ et al. (2003). "GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins". Mol. Cell. Biol. 23 (7): 2476–2488. doi:10.1128/MCB.23.7.2476-2488.2003. PMC 150724. PMID 12640130. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=150724.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.