| CD200 molecule | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | CD200; MOX1; MOX2; MRC; OX-2 | ||||||||||||
| External IDs | OMIM: 155970 MGI: 1196990 HomoloGene: 4344 GeneCards: CD200 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 4345 | 17470 | |||||||||||
| Ensembl | ENSG00000091972 | ENSMUSG00000022661 | |||||||||||
| UniProt | P41217 | Q05D16 | |||||||||||
| RefSeq (mRNA) | NM_001004196.2 | NM_010818.3 | |||||||||||
| RefSeq (protein) | NP_001004196.2 | NP_034948.3 | |||||||||||
| Location (UCSC) | Chr 3: 112.05 – 112.08 Mb |
Chr 16: 45.38 – 45.41 Mb |
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| PubMed search | [1] | [2] | |||||||||||
CD200 (Cluster of Differentiation 200) is a human protein encoded by the CD200 gene.[1]
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.[1]
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.