CALN1

Calneuron 1

Identifiers

External IDs

OMIM: 607176 MGI: 2155987 HomoloGene: 10966 GeneCards: CALN1 Gene

Gene Ontology
Molecular function	• calcium ion binding
Cellular component	• cytoplasm • Golgi apparatus • plasma membrane • integral to membrane • perinuclear region of cytoplasm
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 7:
71.24 – 71.91 Mb

Chr 5:
130.85 – 131.32 Mb

PubMed search

[1]

[2]

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.^[1]^[2]

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites^[3]. Alternative splicing results in multiple transcript variants.^[2]

References

^ Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Mol Genet Metab 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.
^ ^a ^b "Entrez Gene: CALN1 calneuron 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83698.
^ McCue HV, Haynes JW, Burgoyne RD. (2010). "The diversity of calcium sensor proteins in the regulation of neuronal function.". Cold Spring Harb Perspect Biol. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMID 20668007.

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Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139146.
"Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2882961.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.

CALN1

References

Further reading