Butaxamine

Butaxamine
Systematic (IUPAC) name
(1S,2S)-1-(2,5-dimethoxyphenyl)-2-
(tert-butylamino)propan-1-ol
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 2922-20-5
ATC code None
PubChem CID 21909
ChemSpider 20593 Y
UNII 0NM31M53PW Y
Chemical data
Formula C15H25NO3 
Mol. mass 267.364 g/mol
SMILES eMolecules & PubChem
 Y(what is this?)  (verify)

Butaxamine (INN, also known as butoxamine) is a β2-selective beta blocker.[1][2] Its primary use is in experimental situations in which blockade of β2 receptors is necessary to determine the activity of the drug (i.e. if the β2 receptor is completely blocked, but the given effect is still present, the given effect is not a characteristic of the β2 receptor). It has no common clinical use.

An alternative name is α-(1-[t-Butylamino]ethyl)-2,5-dimethoxybenzyl alcohol.

See also

References

  1. ^ "Definition: butoxamine from Online Medical Dictionary". http://cancerweb.ncl.ac.uk/cgi-bin/omd?butoxamine. 
  2. ^ Hillman KL, Doze VA, Porter JE (August 2005). "Functional characterization of the beta-adrenergic receptor subtypes expressed by CA1 pyramidal cells in the rat hippocampus". J. Pharmacol. Exp. Ther. 314 (2): 561–7. doi:10.1124/jpet.105.084947. PMID 15908513. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=15908513. 
Beta, nonselective
Alprenolol  • Bopindolol  • Bupranolol  • Carteolol  • Cloranolol  • Mepindolol  • Nadolol  • Oxprenolol  • Penbutolol  • Pindolol  • Propranolol  • Sotalol  • Tertatolol  • Timolol
Beta1 selective
Acebutolol  • Atenolol  • Betaxolol  • Bevantolol  • Bisoprolol  • Celiprolol  • Epanolol  • Esmolol  • Nebivolol  • Metoprolol  • Practolol  • S-atenolol  • Talinolol
Alpha + beta
Other/ungrouped
Butaxamine

M: VAS

anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)