Benign symmetric lipomatosis
Benign symmetric lipomatosis |
Classification and external resources |
A young man with benign symmetric lipomatosis (Madelung's disease) of idiopathic etiology |
ICD-10 |
E88.8 (ILDS E88.820) |
Benign symmetric lipomatosis (also known as Benign symmetric lipomatosis of Launois–Bensaude and Madelung's disease) is a cutaneous condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area.[1] Named after German surgeon Otto Wilhelm Madelung who was the first to give a detailed description of it, the condition is very rare with an estimated incidence rate of 1 in 25,000 and affecting males up to 30 times more frequently than females.[2] The etiology of the disease remains unknown, but there is a strong correlation with alcohol abuse. Traditionally the treatment is mainly surgical consisting of the removal of the lipomas, although recent study has proposed Phosphatidylcholine injection as a possible alternative.[3]
See also
References
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ González-García R, Rodríguez-Campo FJ, Sastre-Pérez J, Muñoz-Guerra MF (2004). "Benign symmetric lipomatosis (Madelung's disease): case reports and current management". Aesthetic Plast Surg 28 (2): 108–12; discussion 113. doi:10.1007/s00266-004-3123-5. PMID 15164232.
- ^ Hasegawa T, Matsukura T, Ikeda S (June 2009). "Mesotherapy for Benign Symmetric Lipomatosis". Aesthetic Plast Surg 34 (2): 153–6. doi:10.1007/s00266-009-9374-4. PMID 19488808.