BTF3
Transcription factor BTF3 is a protein that in humans is encoded by the BTF3 gene.[1][2][3][4]
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.[4]
Interactions
BTF3 has been shown to interact with CSNK2B.[5]
References
Further reading
- Wiedmann B, Sakai H, Davis TA, Wiedmann M (1994). "A protein complex required for signal-sequence-specific sorting and translocation". Nature 370 (6489): 434–40. doi:10.1038/370434a0. PMID 8047162.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Grein S, Pyerin W (1999). "BTF3 is a potential new substrate of protein kinase CK2". Mol. Cell. Biochem. 191 (1–2): 121–8. doi:10.1023/A:1006806226764. PMID 10094400.
- Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Kusumawidjaja G, Kayed H, Giese N, et al. (2007). "Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells". Cancer Biol. Ther. 6 (3): 367–76. doi:10.4161/cbt.6.3.3704. PMID 17312387.