BST1

Bone marrow stromal cell antigen 1

PDB rendering based on 1isf.
Identifiers
Symbols BST1; CD157
External IDs OMIM600387 MGI105370 HomoloGene3198 GeneCards: BST1 Gene
EC number 3.2.2.5
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 683 12182
Ensembl ENSG00000109743 ENSMUSG00000029082
UniProt Q10588 Q64277
RefSeq (mRNA) NM_004334 NM_009763.3
RefSeq (protein) NP_004325 NP_033893.2
Location (UCSC) Chr 4:
15.7 – 15.74 Mb
Chr 5:
44.21 – 44.23 Mb
PubMed search [1] [2]

ADP-ribosyl cyclase 2 is an enzyme that in humans is encoded by the BST1 gene.[1][2]

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.[2]

See also

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.