| Systematic (IUPAC) name | |
|---|---|
| Diphenyl(piperidin-4-yl)methanol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ℞ Prescription only |
| Routes | Oral |
| Identifiers | |
| CAS number | 115-46-8 1798-50-1 (HCl) |
| ATC code | None |
| PubChem | CID 15723 |
| ChemSpider | 14952 |
| UNII | 2MMR990PEM |
| ChEMBL | CHEMBL127508 |
| Synonyms | MER-17, MDL-4,829 |
| Chemical data | |
| Formula | C18H21NO |
| Mol. mass | 267.37 g/mol |
| SMILES | eMolecules & PubChem |
|
|
| (what is this?) (verify) |
|
Azacyclonol (trade names Ataractan, Calmeran, Frenoton, Frenquel, Psychosan), also known as γ-pipradol, is a drug which is a so-called ataractive, or agent which diminishes hallucinations in psychotic individuals.[1][2] It has also been called a tranquilizer and antipsychotic, though these definitions are not accurate as it does not actually possess such properties. Despite being a positional isomer of pipradrol, it is not a psychostimulant, and instead has mild depressant effects.[1][3]
The drug was introduced in Europe in the mid 1950s for the treatment of schizophrenia likely on account of the fact that it was found to attenuate the subjective psychedelic effects of LSD and mescaline in humans.[1][4] However, due to poor and mixed clinical effectiveness[4] it never gained widespread acceptance and was eventually discontinued.
The antihistamine agent terfenadine produces azacyclonol as an active major metabolite.[5]