Amezinium metilsulfate

Amezinium metilsulfate

Systematic (IUPAC) name
6-Methoxy-1-phenylpyridazin-1-ium-4-amine; methyl sulfate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	30578-37-1^N
ATC code	C01CA25
PubChem	CID 71926
ChemSpider	64937^Y
UNII	03NR868ICX^N
KEGG	D01304^Y
Chemical data
Formula	C₁₂H₁₅N₃O₅S
Mol. mass	313.32 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4)^Y Key:ZEASXVYVFFXULL-UHFFFAOYSA-N^Y
N(what is this?) (verify)

Amezinium metilsulfate (INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.^[1]^[2]

References

^ Araújo, D; Caramona, MM; Osswald, W (1983). "On the mechanism of action of amezinium methylsulphate on the dog saphenous vein". European journal of pharmacology 90 (2-3): 203–14. doi:10.1016/0014-2999(83)90238-8. PMID 6873182. edit
^ Lenke, D; Gries, J; Kretzschmar, R (1981). "Pharmacology of amezinium, a novel antihypotensive drug. III. Studies on the mechanism of action". Arzneimittel-Forschung 31 (9a): 1558–65. PMID 7197970. edit

Cardiac stimulants excluding cardiac glycosides (C01C)

α	Metaraminol • Phenylephrine • Methoxamine • Norfenefrine • Oxedrine • Midodrine • Mephentermine

β	Dobutamine • Arbutamine • Isoprenaline • Prenalterol

mixed	Amezinium metilsulfate • Epinephrine # • Norepinephrine • Etilefrine

Both

Unknown/ungrouped

Other cardiac stimulants

anat/phys/devp

noco/cong/tumr, sysi/epon, injr

proc, drug (C1A/1B/1C/1D), blte