Ambazone[1] | |
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[4-(2-(Diaminomethylidene)hydrazinyl)phenyl]iminothiourea |
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Other names
2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]-Hydrazinecarbothioamide; (4-Oxo-2,5-cyclohexadien-1-ylideneamino)guanidine thiosemicarbazone; 1,4-Benzoquinone amidinohydrazone thiosemicarbazone; Ambazon; Anginon; Benzoquinone guanylhydrazone thiosemicarbazone; Faringosept; Guanothiazon; Inversal; Inversal; Ivertol; N-Guanidino-N'-thioureido-p-benzoquinonediimide; Primal; p-Benzoquinone amidinohydrazone thiosemicarbazone;Faringosept (TN); Ambazone (INN); OAMBAZONE; Ambazonum [INN-Latin]; Ambazona [INN-Spanish]; Ambazone [INN:BAN:DCF]; CCRIS 1926; MLS001240207 |
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Identifiers | |
CAS number | 539-21-9 |
PubChem | 1549158 |
ChemSpider | 12232507 |
EC number | 208-713-0 |
KEGG | D07376 |
ATC code | R02 |
Jmol-3D images | Image 1 |
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Properties | |
Molecular formula | C8H11N7S |
Molar mass | 237.28 g/mol |
Appearance | Dark Brown Powder |
Solubility in water | 0.2 mg/100 ml water |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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Infobox references |
Ambazone is an oral antiseptic 1,4-Benzoquinone guanylhydrazone thiosemicarbazone, better known as Ambazone (C8H11N7S) has a molecular mass of 255.32 g/mol
Contents[hide] |
Bacteriostatic action on hemolytic streptococcus, streptococcus pneumoniae and viridans streptococcus.
Table 1. Physical Properties |
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Dark Brown |
Odorless |
Tasteless |
Powder |
Melting Point 192-194 C |
Table 2. Solubility | per 100 ml |
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Water | 0.2 mg |
Methanol | 0.5 mg |
Chloroform | 0.3 mg |
1-butanol | 6.5 mg |
Ethyl Acetate | 17 mg |
Acetone | 50 mg |
Ethanol | 85 mg |
Di-methyl Formamide | 1.7 g |
sulfoxide | 2.5 g |
Table 3. Uv-Vis | nm |
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water | 403 |
Alcohols | 440-445 |
Ethyl Acetate | 453 |
Di-methyl Sulfoxide | 467 |
Ambazone is prepared by way of solid based crystallization or grinding4.
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