Aloe emodin

Aloe emodin

Systematic (IUPAC) name
1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
Clinical data
Pregnancy cat.	?
Legal status	?
Routes	Oral
Identifiers
CAS number	481-72-1^Y
ATC code	None
PubChem	CID 10207
ChemSpider	9792^Y
KEGG	C10294^Y
ChEMBL	CHEMBL40275^Y
Chemical data
Formula	C₁₅H₁₀O₅
Mol. mass	270.24
SMILES	eMolecules & PubChem
InChI InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2^Y Key:YDQWDHRMZQUTBA-UHFFFAOYSA-N^Y
Physical data
Melt. point	223–224 °C (433–435 °F) Sublimes in CO₂ stream
Y(what is this?) (verify)

Aloe emodin is a carcinogenic^[1]^[2] anthraquinone present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.^[3]

References

^ Badgwell, DB; Walker, CM; Baker, WT; Strickland, FM (2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular carcinogenesis 39 (3): 127–38. doi:10.1002/mc.10170. PMID 14991742.
^ National Toxicology, Program (2010). "Photocarcinogenesis study of aloe vera CAS NO. 481-72-1(Aloe-emodin) in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program technical report series (553): 7–33, 35–97, 99–103 passim. PMID 21031007.
^ The Merck Index, 12th Edition. 313.

Types of anthraquinones

Hydroxyanthraquinones	\|

Dihydroxyanthraquinones	Alizarin \| Aloe emodin \| Damnacanthal \| 1,3-Dihydroxyanthraquinone \| 1,4-Dihydroxyanthraquinone \| 1,8-Dihydroxyanthraquinone \| Rhein

Trihydroxyanthraquinones	Parietin \| Emodin

Tetrahydroxyanthraquinones	1,2,4-Trihydroxyanthraquinone \| 1,3,8-Trihydroxyanthraquinone

Pentahydroxyanthraquinones	\|

Hexahydroxyanthraquinones	\|

Heptahydroxyanthraquinones	\|

Misc:	Anthraquinone drugs \| Anthraquinone dyes Carminic acid \| 2-Ethylanthraquinone \| Quinalizarin \| Rufigallol \| Senna glycosides \| Sodium 2-anthraquinonesulfonate

Aloe emodin

References

See also