Systematic (IUPAC) name | |
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(RS)-4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one | |
Clinical data | |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
Pregnancy cat. | X |
Legal status | POM (UK) |
Routes | Oral |
Pharmacokinetic data | |
Metabolism | Hepatic |
Half-life | 8 to 11 hours |
Identifiers | |
CAS number | 152-72-7 |
ATC code | B01AA07 |
PubChem | CID 9052 |
DrugBank | DB01418 |
ChemSpider | 10443441 |
UNII | I6WP63U32H |
KEGG | D07064 |
ChEBI | CHEBI:53766 |
ChEMBL | CHEMBL397420 |
Chemical data | |
Formula | C19H15NO6 |
Mol. mass | 353.326 g·mol-1 |
SMILES | eMolecules & PubChem |
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(what is this?)
Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is marketed under the brand names Sintrom and Sinthrome.
Research in the RECAVA network has discovered that two acquired factors (age and body mass index) and three genetic polymorphisms (genes VKORC1, CYP2C9 and CYP4F2) are useful to establish the right dosage. Acenocoumarol is contraindicated during pregnancy.
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