ASCC3

Activating signal cointegrator 1 complex subunit 3

Identifiers

ASCC3; ASC1p200; DJ467N11.1; HELIC1; MGC26074; RNAH; dJ121G13.4

External IDs

MGI: 1925237 HomoloGene: 4973 GeneCards: ASCC3 Gene

Gene Ontology
Molecular function	• nucleotide binding • nucleic acid binding • helicase activity • ATP binding • ATP-dependent helicase activity • hydrolase activity
Cellular component	• intracellular • cytoplasm • microtubule cytoskeleton
Biological process	• regulation of transcription, DNA-dependent
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000112249

ENSMUSG00000038774

n/a

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 6:
100.96 – 101.33 Mb

Chr 10:
50.31 – 50.57 Mb

PubMed search

Activating signal cointegrator 1 complex subunit 3 is a protein that in humans is encoded by the ASCC3 gene.^[1]^[2]

Interactions

ASCC3 has been shown to interact with RELA,^[3] C-jun^[3] and Serum response factor.^[3]

References

^ Coulie PG, Ikeda H, Baurain JF, Chiari R (Jun 1999). "Antitumor immunity at work in a melanoma patient". Adv Cancer Res. Advances in Cancer Research 76: 213–42. doi:10.1016/S0065-230X(08)60778-2. ISBN 9780120066766. PMID 10218103.
^ "Entrez Gene: ASCC3 activating signal cointegrator 1 complex subunit 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10973.
^ ^a ^b ^c Jung, Dong-Ju; Sung Hee-Sook, Goo Young-Wha, Lee Hyun Mi, Park Ok Ku, Jung Sung-Yun, Lim Janghoo, Kim Han-Jong, Lee Soo-Kyung, Kim Tae Sung, Lee Jae Woon, Lee Young Chul (Jul. 2002). "Novel Transcription Coactivator Complex Containing Activating Signal Cointegrator 1". Mol. Cell. Biol. (United States) 22 (14): 5203–11. doi:10.1128/MCB.22.14.5203-5211.2002. ISSN 0270-7306. PMC 139772. PMID 12077347. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139772.

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1083732.
Jung DJ, Sung HS, Goo YW, et al. (2002). "Novel Transcription Coactivator Complex Containing Activating Signal Cointegrator 1". Mol. Cell. Biol. 22 (14): 5203–11. doi:10.1128/MCB.22.14.5203-5211.2002. PMC 139772. PMID 12077347. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139772.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528930.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1347501.