ARACNE

ARACNE (Algorithm for the Reconstruction of Accurate Cellular Networks) is a method for reconstructing biological networks from microarray data developed at Columbia University. The method uses information theoretic methods to reduce false positives which are predicted through indirect interactions[1][2].

References

  1. ^ Margolin, A., Nemenman, I., Basso, K., Wiggins, C., Stolovitzky, G., Favera, R. and Califano, A. (2006). "ARACNE: an Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context". BMC bioinformatics 7 (Suppl 1): S7. 
  2. ^ "Software/ARACNE - Califano Lab". http://wiki.c2b2.columbia.edu/califanolab/index.php/Software/ARACNE. Retrieved 18 August 2010.