ALG11

Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)

Identifiers

ALG11; CDG1P; GT8; KIAA0266

External IDs

OMIM: 613666 MGI: 2142632 HomoloGene: 68893 GeneCards: ALG11 Gene

Gene Ontology
Molecular function	• protein binding • transferase activity, transferring hexosyl groups
Cellular component	• endoplasmic reticulum • endoplasmic reticulum membrane • membrane • integral to membrane
Biological process	• dolichol-linked oligosaccharide biosynthetic process • biosynthetic process • protein N-linked glycosylation via asparagine • post-translational protein modification • cellular protein metabolic process
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

ENSG00000253710

ENSMUSG00000063362

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 13:
52.59 – 52.6 Mb

Chr 8:
23.17 – 23.18 Mb

PubMed search

Asparagine-linked glycosylation protein 11 homolog is an enzyme that in humans is encoded by the ALG11 gene.^[1]

See also

Congenital disorder of glycosylation

References

^ "Entrez Gene: asparagine-linked glycosylation 11". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=440138.

Further reading

Rohozinski J, Lamb DJ, Bishop CE (2006). "UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man.". Biol. Reprod. 74 (4): 644–51. doi:10.1095/biolreprod.105.046698. PMID 16354793.
Rind N, Schmeiser V, Thiel C, et al. (2010). "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.". Hum. Mol. Genet. 19 (8): 1413–24. doi:10.1093/hmg/ddq016. PMID 20080937.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.