ADH4

Alcohol dehydrogenase 4 (class II), pi polypeptide
Identifiers
Symbols ADH4; ADH-2
External IDs OMIM103740 MGI1349472 HomoloGene20162 GeneCards: ADH4 Gene
EC number 1.1.1.1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 127 26876
Ensembl ENSG00000198099 ENSMUSG00000037797
UniProt P08319 Q3V0P5
RefSeq (mRNA) NM_000670 NM_011996.2
RefSeq (protein) NP_000661 NP_036126.2
Location (UCSC) Chr 4:
100.04 – 100.08 Mb
Chr 3:
138.08 – 138.09 Mb
PubMed search [1] [2]

Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene.[1]

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.[1]

References

Further reading