| 4-Hydroxy-3-nitrobenzenearsonic acid | |
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4-Hydroxy-3-nitrobenzenearsonic acid |
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(4-Hydroxy-3-nitrophenyl)arsonic acid[1] |
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Other names
3-Nitro-4-hydroxyphenyl arsonic acid |
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| Identifiers | |
| CAS number | 121-19-7 |
| PubChem | 5104 |
| ChemSpider | 4925 |
| EC number | 204-453-7 |
| UN number | 3465 |
| KEGG | D05771 |
| MeSH | Roxarsone |
| ChEBI | CHEBI:35817 |
| RTECS number | CY5250000 |
| Beilstein Reference | 1976533 |
| Gmelin Reference | 1221211 |
| Jmol-3D images | Image 1 Image 2 |
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| Properties | |
| Molecular formula | C6AsNH6O6 |
| Molar mass | 263.0365 g mol-1 |
| Exact mass | 262.941108346 g mol-1 |
| Melting point |
>300 °C |
| Hazards | |
| GHS pictograms | |
| GHS signal word | DANGER |
| GHS hazard statements | H301, H331, H410 |
| GHS precautionary statements | P261, P273, P301+310, P311, P501 |
| EU classification | T N |
| R-phrases | R23/25, R50/53 |
| S-phrases | S20/21, S28, S45, S60, S61 |
| (verify) (what is: /?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
4-Hydroxy-3-nitrobenzenearsonic acid is an organic compound that is widely used agriculturally as a chicken-feed additive. The molecule is a derivative of phenylarsonic acid (C6H5As(O)(OH)2). This organoarsenic compound, usually under the tradename Roxarsone, has attracted attention as a source of arsenic contamination of the food chain. Approximately 1 million kilograms of this compound was produced in 2006 in the US.[2] This compound was first reported in a 1923 British patent which describes the nitration and diazotization of arsanilic acid.[3] This compound when blended with calcite powder, is widely used to make feed premixes in the poultry industry and is usually available in 5%, 20% and 50% concentrations.
In June 2011, the FDA has given Pfizer 30 days to discontinue selling this product; the FDA's findings indicated high levels of arsenic in these chickens consuming the arsonic acid.[4]