3-Nitrobenzanthrone

3-Nitrobenzanthrone
IUPAC name

3-Nitro-3,3a-dihydro-benzo[de]anthracen-7-one
Identifiers
CAS number 17117-34-9
ChemSpider 2103821 Y
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C17H9NO3
Molar mass 275.26 g/mol
Melting point

248 °C[1]
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

3-Nitrobenzanthrone (3-nitro-7H-benz[de]anthracen-7-one) is a chemical compound emitted in diesel exhaust; it is a potent carcinogen.[2] It produced the highest score ever reported in the Ames test, a standard measure of the cancer-causing potential of toxic chemicals, far greater than the previous known strongest 1,8-dinitropyrene which also found in diesel exhaust.[3]

See also

References

  1. ^ Hansen, Tanja; Seidel, Albrecht; Borlak, Juergen (2007). "The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells". Toxicology and Applied Pharmacology 221 (2): 222–234. doi:10.1016/j.taap.2007.03.003. PMID 17477947. 
  2. ^ Volker M. Arlt (2005). "3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence". Mutagenesis 20 (6): 399–410. doi:10.1093/mutage/gei057. PMID 16199526. http://mutage.oxfordjournals.org/cgi/reprint/20/6/399. 
  3. ^ Fred Pearce (Oct 25, 1997). "Devil in the diesel". New Scientist: 4. http://www.newscientist.com/article/mg15621050.200-devil-in-the-diesel--lorries-belch-out-what-may-be-the-most.html.