2-Aminopyridine

2-Aminopyridine

IUPAC name Pyridin-2-amine
Other names 2-Pyridinamine; 2-Pyridylamine; α-Aminopyridine
Identifiers
CAS number	504-29-0^Y
PubChem	10439
ChemSpider	10008^Y
ChEMBL	CHEMBL21619^Y
Jmol-3D images	Image 1 Image 2
SMILES n1ccccc1N c1ccnc(c1)N
InChI InChI=1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)^Y Key: ICSNLGPSRYBMBD-UHFFFAOYSA-N^Y InChI=1/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7) Key: ICSNLGPSRYBMBD-UHFFFAOYAM
Properties
Molecular formula	C₅H₆N₂
Molar mass	94.11 g mol⁻¹
Appearance	colourless solid
Melting point	59-60 °C
Boiling point	210 °C
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2-Aminopyridine is an organic compound with the formula H₂NC₅H₄N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.^[1]

Structure

Although 2-hydroxypyridine exists in significant amounts as the pyridone tautomer, the related imine tautomer (HNC₅H₄NH) is less important for 2-aminopyridine.

References

^ Shinkichi Shimizu, Nanao Watanabe, Toshiaki Kataoka, Takayuki Shoji, Nobuyuki Abe, Sinji Morishita, Hisao Ichimura "Pyridine and Pyridine Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry 2000, Wiley-VCH, Weinheim. doi:10.1002/14356007.a22_399

External links

MSDS