2,3-Dichlorophenylpiperazine

2,3-Dichlorophenylpiperazine
IUPAC name

1-(2,3-dichlorophenyl)piperazine
Identifiers
CAS number 41202-77-1
PubChem 851833
ChemSpider 744460 Y
Jmol-3D images Image 1
Properties
Molecular formula C10H12Cl2N2
Molar mass 231.12 g/mol
Appearance brown oil
Density 1.272g/cm3 °C
Melting point

242-244°C
Boiling point

365.1°C @ 760mmHg
Hazards
Flash point 174.6°C
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2,3-Dichlorophenylpiperazine (2,3-DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites.[1][2] It is unknown whether 2,3-DCPP is pharmacologically active similarly to its close analogue 3-chlorophenylpiperazine (mCPP).

See also

References

  1. ^ Leś A, Badowska-Rosłonek K, Łaszcz M, Kamieńska-Duda A, Baran P, Kaczmarek Ł (2010). "Optimization of aripiprazole synthesis". Acta Poloniae Pharmaceutica 67 (2): 151–7. PMID 20369792. 
  2. ^ Caccia S (August 2007). "N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed". Current Drug Metabolism 8 (6): 612–22. doi:10.2174/138920007781368908. PMID 17691920. http://www.bentham-direct.org/pages/content.php?CDM/2007/00000008/00000006/0005F.SGM.