1,2-Naphthoquinone

1,2-Naphthoquinone
Identifiers
CAS number 524-42-5 Y
PubChem 10667
ChemSpider 10217 Y
KEGG C14783 Y
ChEMBL CHEMBL52347 N
Jmol-3D images Image 1
Properties
Molecular formula C10H6O2
 N (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

'1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula C10H6O2.

This double ketone (quinone) is a reactive metabolite of naphthalene and is found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.[1]

See also

References

  1. ^ Qian W, Shichi H (August 2001). "Naphthoquinone-Induced cataract in mice: possible involvement of Ca2+ release and calpain activation". J Ocul Pharmacol Ther 17 (4): 383–92. doi:10.1089/108076801753162799. PMID 11572469. 

External links