Talk:Zygomycosis

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Phycomycosis was merged into this article see it's talk page for historical reference. Basidiobolomycosis was merged into this article see it's talk page for historical reference.

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[edit] Iron

doi:10.1172/JCI32338 - in mice, removing iron by chelation with deferasirox makes it go away. Interesting. JFW | T@lk 14:56, 10 September 2007 (UTC)

doi:10.1128/CMR.18.3.556-569.2005 is a recent review that could inform further improvements in this article. JFW | T@lk 22:13, 20 January 2008 (UTC)

[edit] Pulmonary Embolism

In regards to your edit which removed this from the differentials mentioned at the beginning of the article, I listed PE because it was listed under the eMedicine article as a differential. Admittedly, it has only a vague resemblance to mucormycosis, but I believe the author was referring to some similar symptoms which are generally quite common, e.g. cough, edema, dyspnea etc. Due to the familiarity of these symptoms with a wide range of diseases, I see your reasoning for removing it! CycloneNimrod (talk) 22:52, 20 January 2008 (UTC)

[edit] Name change

Should the name of the article be changed to Zygomycosis over Mucormycosis? I was reading: http://www.doctorfungus.org/thefungi/zygomycetes.htm . And it got me thinking of what the main article name should be. I like it how it is, but if zygomycosis truly is the more common name, should we switch it? §hep • ¡Talk to me! 22:59, 21 April 2008 (UTC)

It's more of an issue of personal preference (as far as I can tell). Different sources state different names as their primary name for the condition. Best not to move it until there's a definite need to change. Regards, CycloneNimrod^Talk? 17:57, 22 April 2008 (UTC)

Sounds good to me. §hep • ¡Talk to me! 20:32, 23 April 2008 (UTC)

[edit] Merge

The result was merge into Mucormycosis. -- §hep  •  ¡Talk to me! 21:14, 5 May 2008 (UTC)

[edit] After the merge, perhaps a name change

From what I can tell, zygomycosis seems like the correct term. All other articles seem to mention zycomycetes at the bacteria which cause these diseases.. Regards, CycloneNimrod^Talk? 20:14, 6 May 2008 (UTC)

Sounds good (note above discussion). I tried to move the page but Zygomycosis already redirects here and will need to be done by an admin. §hep • ¡Talk to me! 23:04, 6 May 2008 (UTC)

[edit] Ideas

I have a few ideas I thought I'd toss out before going at it. Should a majority of the word Mucormycosis be replaced with Zygomycosis? If so AWB can handle that. Also, do we really need the section titled Zygomycosis or could it be merged with other sections. It just seems funny to have a section of the article with the article title. §hep • ¡Talk to me! 20:09, 7 May 2008 (UTC)

I agree. I'll sort it out now. Regards, CycloneNimrod^Talk? 19:22, 10 May 2008 (UTC)

[edit] PR as requested

Cyclonenim asked me to do this PR. A very nice article, definitely not a start class! Here are a few thoughts, hope this is what you were looking for:

• Define unfamiliar words like "oropharyngeal cavity", "orbitorhinocerebral", "rhinocerebral disease", "dyspnea", "fungal hyphae"

Y Done Regards, CycloneNimrod^Talk? 13:20, 16 May 2008 (UTC)

• I think the lead could use some expansion and organization: maybe a paragraph on types of fungi that cause it, then a paragraph on the condition, with signs and symptoms and the 'rapidly spreading' fact, treatment, prognosis etc.

Y Done Regards, CycloneNimrod^Talk? 06:48, 16 May 2008 (UTC)

• The "Cause" section is very small, could you expand it or integrate it into another section?

Y Done Regards, CycloneNimrod^Talk? 13:20, 16 May 2008 (UTC)

• "infarction/necrosis" - avoid slashes when possible, they're ambiguous. Does this mean infarction or necrosis? Or an entity that involves both infarction and necrosis? Best to specify. Same with "nausea/vomiting".

Y Done Regards, CycloneNimrod^Talk? 13:20, 16 May 2008 (UTC)

• "The lack of case reports regarding maxillofacial zygomycosis lies in the rich vascularity of the maxillofacial areas preventing fungal infections, although this can be overcome by more prevalent fungi, bacteria or viruses such as those responsible for zygomycosis." awkward.

Y Done Regards, CycloneNimrod^Talk? 13:20, 16 May 2008 (UTC)

• These paragraphs don't belong in the 'signs and symptoms' section: maxilla, Predisposing factors, complications, and Basidiobolomycosis. The latter can probably go in diagnosis, as it's a differential. Complications can go in the "prognosis" section. Predisposing factors can go in "Epidemiology", there's already a sentence there with other factors. The others would ideally be their own sections, but they're currently too short. I don't know about the advisability of creating a catchall "Features" section, maybe ask at WT:MED or a more clueful WP:MED member.

Pretty much Y Done, just Maxilla paragraph that needs a new home. Regards, CycloneNimrod^Talk? 13:28, 16 May 2008 (UTC)

How about this? At least now it's in a paragraph about places it can occur. delldot talk 13:09, 19 May 2008 (UTC)

• "Computerised imaging techniques such as MRIs, CT scans and X-rays" are X-rays computerized?

Y Done - They can be. Regards, CycloneNimrod^Talk? 13:20, 16 May 2008 (UTC)

• "Differentials to consider in diagnosis of the infection include anthrax, aspergillosis and cellulitis" Reads like a how to for docs. Also, too technical, the lay reader probably won't understand: either define differentials or word it in layperson's terms, e.g. "Zygomycosis can be confused for other conditions with similar signs and symptoms, including..."

Y Done Regards, CycloneNimrod^Talk? 13:58, 16 May 2008 (UTC)

• One sentence paragraphs are discouraged, consider combining or expanding some of them.

Y Done Regards, CycloneNimrod^Talk? 13:58, 16 May 2008 (UTC)

• Explain "ghosts on the slide"

Y Done Regards, CycloneNimrod^Talk? 13:58, 16 May 2008 (UTC)

• The last paragraph under Diagnosis is unreferenced.

Y Done Regards, CycloneNimrod^Talk? 13:58, 16 May 2008 (UTC)

• I, for one, could use a clearer explanation of how basidiobolomycosis relates to Zygomycosis.

Doing... From The Center of Disease Control Basidiobolomycosis is a form of zygomycosis caused by the fungus B. ranarum (from the order Entomophthorales), which has been isolated throughout the world from decaying vegetation and soil and from the GI tracts of reptiles, amphibians, fish, and insectivorous bats §hep • ¡Talk to me! 19:26, 18 May 2008 (UTC)

• "If zygomycosis is suspected, prompt amphotericin B therapy should be administered due to the rapid spread and mortality rate of the disease." reads like a how to for docs.
• Use en dashes (–) rather than hyphens (-) for number ranges per WP:DASH.

Y Done Fixed the two instances. §hep • ¡Talk to me! 19:26, 18 May 2008 (UTC)

• I would organize the "Treatment" section into three paragraphs: Drugs, surgery, and other. Currently there's a little of each mixed up in each paragraph.
• It's difficult to keep separate all the conditions or understand how they relate to each other. Maybe a classification section would work, where Pythiosis and all the other types are described. If not that, have a lead sentence in the Pythiosis section explaining how it relates.
• The paragraph beginning "It is suspected that pythiosis is caused..." needs more references.
• A lot of your references are primary sources, case reports, or websites like emedicine: not the best sources. Good job finding some textbooks and journal reviews though, it's best to rely most heavily on those.

These are just suggestions, if you have a reason not to implement them then no problem. I'd work mainly on the readability, putting more sentences in layperson's terms, and getting more secondary and tertiary sources. I didn't see any NPOV problems, I'm not sure what I was supposed to be looking for there though. Let me know if this helps or if you need something more specific. Definitely drop me a note if you want more clarification or help with anything. delldot talk 04:51, 15 May 2008 (UTC)

Delldot, I numbered your comments for ease of responding to one of them:

On #7: X-rays can be evaluated by computer. See Computer-aided diagnosis. WhatamIdoing (talk) 22:58, 15 May 2008 (UTC)

Thanks for clearing that up!  :) delldot talk 13:09, 19 May 2008 (UTC)

Awesome work, folks. The lead is beautiful. One more thing I noticed just now: "The clinical hallmark of zygomycosis is vascular invasion resulting in thrombosis and tissue infarction and necrosis. If cerebral disease is the cause of the infection, symptoms may include unilateral, retro-orbital headache..." Both of these sentences should be reworded for the lay reader. Wording that should be explained or replaced includes "clinical hallmark", "vascular invasion", "thrombosis", "infarction", "necrosis", "cerebral disease", and "unilateral, retro-orbital headache". Also, what does "protrusion of eye o::rbit" mean? delldot talk 13:09, 19 May 2008 (UTC)

Y Done - I hope it's easier to understand now, delldot! :) Regards, CycloneNimrod^Talk? 20:37, 19 May 2008 (UTC)