ZKSCAN5

From Wikipedia, the free encyclopedia

Zinc finger with KRAB and SCAN domains 5

Identifiers

ZKSCAN5; FLJ39233; KIAA1015; MGC33710; ZFP95

External IDs

Gene ontology
Molecular Function:	• transcription factor activity • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014569 (mRNA)
NP_055384 (protein)

NM_016683 (mRNA)
NP_057892 (protein)

Location

Chr 7: 98.94 - 98.97 Mb

Chr 5: 145.46 - 145.47 Mb

Pubmed search

[1]

[2]

Zinc finger with KRAB and SCAN domains 5, also known as ZKSCAN5, is a human gene.^[1]

This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain. A similar protein in mouse is differentially expressed in spermatogenesis. Two alternatively spliced transcript variants differing only in the 5' UTR have been described. Additional variants have been found, but their full-length sequences have not been determined.^[1]

[edit] References

^ ^a ^b Entrez Gene: ZKSCAN5 zinc finger with KRAB and SCAN domains 5.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63-70. PMID 10231032.
Dreyer SD, Zheng Q, Zabel B, et al. (2000). "Isolation, characterization, and mapping of a zinc finger gene, ZFP95, containing both a SCAN box and an alternatively spliced KRAB A domain.". Genomics 62 (1): 119-22. doi:10.1006/geno.1999.5981. PMID 10585779.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster.". Pharmacogenomics J. 6 (2): 105-14. doi:10.1038/sj.tpj.6500347. PMID 16314882.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.