ZFYVE20

From Wikipedia, the free encyclopedia

Zinc finger, FYVE domain containing 20

PDB rendering based on 1yzm.

Available structures: 1yzm, 1z0j, 1z0k

Identifiers

Symbol(s)

ZFYVE20; FLJ34993; MGC126210; Rabenosyn-5

External IDs

OMIM: 609511 MGI: 1925537 HomoloGene: 41477

Gene ontology
Molecular Function:	• nucleic acid binding • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • endosome • membrane
Biological Process:	• protein transport • endosome transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_022340 (mRNA)
NP_071735 (protein)

NM_030081 (mRNA)
NP_084357 (protein)

Location

Chr 3: 15.09 - 15.12 Mb

Chr 6: 92.15 - 92.18 Mb

Pubmed search

[1]

[2]

Zinc finger, FYVE domain containing 20, also known as ZFYVE20, is a human gene.^[1]

[edit] References

^ Entrez Gene: ZFYVE20 zinc finger, FYVE domain containing 20.

[edit] Further reading

Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Eathiraj S, Pan X, Ritacco C, Lambright DG (2005). "Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.". Nature 436 (7049): 415-9. doi:10.1038/nature03798. PMID 16034420.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Naslavsky N, Boehm M, Backlund PS, Caplan S (2005). "Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane.". Mol. Biol. Cell 15 (5): 2410-22. doi:10.1091/mbc.E03-10-0733. PMID 15020713.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
de Renzis S, Sönnichsen B, Zerial M (2002). "Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.". Nat. Cell Biol. 4 (2): 124-33. doi:10.1038/ncb744. PMID 11788822.
Nielsen E, Christoforidis S, Uttenweiler-Joseph S, et al. (2000). "Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain.". J. Cell Biol. 151 (3): 601-12. PMID 11062261.