ZBTB32

From Wikipedia, the free encyclopedia

Zinc finger and BTB domain containing 32

Identifiers

ZBTB32; FAXF; FAZF; Rog; TZFP; ZNF538

External IDs

OMIM: 605859 MGI: 1891838 HomoloGene: 8661

Gene ontology
Molecular Function:	• DNA binding • specific RNA polymerase II transcription factor activity • transcription corepressor activity • protein binding • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• negative regulation of transcription from RNA polymerase II promoter • transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014383 (mRNA)
NP_055198 (protein)

NM_021397 (mRNA)
NP_067372 (protein)

Location

Chr 19: 40.9 - 40.9 Mb

Chr 7: 30.3 - 30.3 Mb

Pubmed search

[1]

[2]

Zinc finger and BTB domain containing 32, also known as ZBTB32, is a human gene.^[1]

[edit] References

^ Entrez Gene: ZBTB32 zinc finger and BTB domain containing 32.

[edit] Further reading

Lin W, Lai CH, Tang CJ, et al. (1999). "Identification and gene structure of a novel human PLZF-related transcription factor gene, TZFP.". Biochem. Biophys. Res. Commun. 264 (3): 789-95. doi:10.1006/bbrc.1999.1594. PMID 10544010.
Hoatlin ME, Zhi Y, Ball H, et al. (1999). "A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.". Blood 94 (11): 3737-47. PMID 10572087.
Tsuzuki S, Enver T (2002). "Interactions of GATA-2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11;17)-generated PLZF-retinoic acid receptor alpha oncoprotein.". Blood 99 (9): 3404-10. PMID 11964310.
Dai MS, Chevallier N, Stone S, et al. (2002). "The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific.". J. Biol. Chem. 277 (29): 26327-34. doi:10.1074/jbc.M201834200. PMID 11986317.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Han SH, Jeon JH, Ju HR, et al. (2003). "VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression.". Oncogene 22 (26): 4035-46. doi:10.1038/sj.onc.1206610. PMID 12821938.
Reuter TY, Medhurst AL, Waisfisz Q, et al. (2003). "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.". Exp. Cell Res. 289 (2): 211-21. PMID 14499622.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Ikeda R, Yoshida K, Inoue I (2007). "Identification of FAZF as a novel BMP2-induced transcription factor during osteoblastic differentiation.". J. Cell. Biochem. 101 (1): 147-54. doi:10.1002/jcb.21165. PMID 17171645.