Z-farnesyl diphosphate synthase
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In enzymology, a Z-farnesyl diphosphate synthase (EC 2.5.1.68) is an enzyme that catalyzes the chemical reaction
- geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
Thus, the two substrates of this enzyme are geranyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and (2Z,6E)-farnesyl diphosphate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase. This enzyme is also called (Z)-farnesyl diphosphate synthase.
[edit] References
- IUBMB entry for 2.5.1.68
- BRENDA references for 2.5.1.68 (Recommended.)
- PubMed references for 2.5.1.68
- PubMed Central references for 2.5.1.68
- Google Scholar references for 2.5.1.68
- F, Bertini S, Brennan PJ, Crick DC (2001). "Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis". J. Biol. Chem. 276: 11624–30. PMID 11152452.
[edit] External links
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