YdaO/yuaA leader

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ydaO/yuaA leader
Template:Abbreviation
Type: Cis-reg;
2° structure: Predicted; Barrick JE, Breaker RR
Seed alignment: Barrick JE, Breaker RR
Avg length: 155.4 nucleotides
Avg identity: 55%

This YdaO/YuaA leader is a conserved RNA structure found upstream of the ydaO and yuaA genes in Bacillus subtilis and related genes in other bacteria. The ydaO/yuaA element is thought to act as a genetic "off" switch for the ydaO and yuaA genes in its native state. It is believed that the element may be triggered during osmotic shock leading to activation of ydaO, a predicted amino acid transporter gene, and members of the yuaA-yubG operon which code for KtrA and KtrB K+ transporters.[1]

[edit] References

  1. ^ Barrick, JE; Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR (2004). "New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control". Proc Natl Acad Sci U S A 101: 6421–6426. doi:10.1073/pnas.0308014101. PMID 15096624. 

[edit] External links