YBX2

From Wikipedia, the free encyclopedia

Y box binding protein 2

PDB rendering based on 1h95.

Available structures: 1h95

Identifiers

Symbol(s)

YBX2; CSDA3; MGC45104; MSY2

External IDs

MGI: 1096372 HomoloGene: 22942

Gene ontology
Molecular Function:	• DNA binding • chromatin binding • mRNA binding • lipid binding • translation regulator activity
Cellular Component:	• nucleus • cytoplasm • ribonucleoprotein complex
Biological Process:	• regulation of transcription, DNA-dependent • transcription from RNA polymerase II promoter • spermatogenesis • spermatid development • translational attenuation • oogenesis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015982 (mRNA)
NP_057066 (protein)

XM_978189 (mRNA)
XP_983283 (protein)

Location

Chr 17: 7.13 - 7.14 Mb

Chr 11: 69.75 - 69.76 Mb

Pubmed search

[1]

[2]

Y box binding protein 2, also known as YBX2, is a human gene.^[1]

[edit] References

^ Entrez Gene: YBX2 Y box binding protein 2.

[edit] Further reading

Hammoud S, Emery BR, Dunn D, et al.. "Sequence alterations in the YBX2 gene are associated with male factor infertility.". Fertil. Steril.. doi:10.1016/j.fertnstert.2008.01.009. PMID 18339382.
Yoshida T, Izumi H, Uchiumi T, et al. (2006). "Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines.". Biochim. Biophys. Acta 1759 (1-2): 80-8. doi:10.1016/j.bbaexp.2006.02.005. PMID 16624424.
Kohno Y, Matsuki Y, Tanimoto A, et al. (2006). "Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen.". Br. J. Cancer 94 (5): 710-6. doi:10.1038/sj.bjc.6602987. PMID 16479255.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Tekur S, Pawlak A, Guellaen G, Hecht NB (1999). "Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization.". J. Androl. 20 (1): 135-44. PMID 10100484.
Gu W, Tekur S, Reinbold R, et al. (1998). "Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2.". Biol. Reprod. 59 (5): 1266-74. PMID 9780336.