Windber Research Institute

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Windber Research Institute or WRI is a private, non-profit biomedical research institute that is focused on women's health, cardiovascular disease and processes of aging, is located on Somerset Avenue in Windber, PA. It opened in 2001.

The research of WRI is mainly divided into tissue banking, data warehousing of clinical, molecular (genomic and proteomic) and imaging data and data analysis and interpretation along with the biomedical informatics team.

Through an existing relationship with the Walter Reed Army Medical Center, in the Clinical Breast Care Program, WRI currently has greater than 14,000 highly annotated breast tissues, alone, with more than 500 data fields and single pathologist review on each patient, integrated with all the molecular and imaging data as well. Studies are ongoing regarding tumor heterogeneity, disease and patient stratification, environment and lifestyle risk factors, ethnicity, and biomarker development, all with a focus on addressing existing clinical problems.

In addition, WRI is examining the impact of lifestyle modification programs, using diet, stress management and exercise along with group support, to reduce cardiovascular risk factors, control obesity and impact diabetes. This is part of the Ornish Lifestyle Program that is offered at Windber.

Its diagnostic capabilities include digital and film mammography, 4-D ultrasound, 16-slice PET/CT and a 3T HD MRI which are integrated into the clinical data, molecular data and image repository.