William Standish Knowles
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| William Standish Knowles | |
| Born | June 1, 1917 Taunton, Massachusetts, United States |
|---|---|
| Nationality | American |
| Fields | Chemist |
| Institutions | Thomas and Hochwalt laboratories, Monsanto |
| Alma mater | Columbia University |
| Doctoral advisor | Robert Elderfield |
| Known for | Chiral phosphine ligands that proved effective in the enantioselective synthesis of L-DOPA |
| Notable awards |  Nobel Prize in Chemistry (2001) (jointly with Ryoji Noyori and K. Barry Sharpless) |
William S. Knowles (born June 1, 1917) is an American chemist. He was born in Taunton, Massachusetts.
He shared the Nobel Prize in Chemistry in 2001 with Ryoji Noyori and K. Barry Sharpless for the development of catalytic asymmetric synthesis, which is a technology relevant to the preparation of many pharmaceuticals. Knowles led a team of researchers that developed chiral phosphine ligands that proved effective in the enantioselective synthesis of L-DOPA.[1][2] Knowles conducted this prize-winning research at Monsanto.
He currently resides in St. Louis, Missouri.
[edit] References
- ^ Vineyard, B. D.; Knowles, W. S.; Sabacky, M. J.; Bachman, G. L.; Weinkauff, D. J. (1977). "Asymmetric Hydrogenation. Rhodium Chiral Bisphosphine Catalyst". Journal of the American Chemical Society 99 (18): 5946–5952. doi:.
- ^ Knowles, W. S. (2002). "Asymmetric Hydrogenations (Nobel Lecture)". Angewandte Chemie International Edition 41: 1998–2007. doi:.
[edit] External links
- Knowles's Nobel Foundation biography
- Knowles's Nobel Lecture Asymmetric Hydrogenations
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