Wikipedia:WikiProject Pharmacology/Workspace

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Contents

[edit] Naming conventions

Done. :) I've gone through the entire list of drugs to find INNs that redirect. Unless I've missed any (which is very possible) they should all be listed on this page. I will let a few days go by for people to raise any concerns then I will move those pages with no objections. Matt 19:29, 24 Dec 2004 (UTC)

[edit] Source document for INNs

What is the primary source document for INNs ? I suggest that it is the WHO Chronicle. A link to an archive of relevant scanned PDF copies containing proposed and recommended INNs can be found at http://www.who.int/druginformation/ -- Derek Ross | Talk 16:39, 2004 Dec 30 (UTC)

[edit] List of names to fix

Here I'm compiling a list of drugs that aren't listed under their INN, because I know that the naming of pages can be a sensitive issue, I'm going to mention my intent on the talk page long before moving the page. I will direct people here for discussion if they object.

  • For the naturally occuring short polypeptides and proteins, when we have the "one gene-one polypeptide" rule, their names should be acording to the NCBI site - http://www.ncbi.nlm.nih.gov/mapview/map_search.cgi?taxid=9606,. While in those cases where a single gene codes the information for several polypeptide chains, as it is with POMK and ACTH, or where the products of several different genes are necessary for the formation of the final functional protein, as it is with the GCB family and GCA, and their product hCG, in these cases we should use their well known abreviations.

[edit] List of INN redirects

This is a list of INNs that redirect to another page but moving has been objected to. Reasons for not moving the page should be included with each entry.

  • meticillin redirects to methicillin
    • Since the drug is no longer widely in clinical use, and it's almost never referred to by its INN, I think methicillin should stay where it is. -Techelf 09:09, 26 January 2006 (UTC)
  • methylcobalamin is a redirect to a page about a different substance. They may be related, but one is not the parent of the other. I disagree with the redirect. Redirects inhibit contribution since as a new user I don't know how to fix it. --Gearspring 14:58, 24 January 2006 (UTC)
  • melagatran redirects to ximelagatran
    • Disagree [to moving page]. Ximelagatran is the oral form, which happens to be biotransformed into melagatran.JFW | T@lk 22:14, 23 Dec 2004 (UTC)
      • Ah, then it's a case of a closely related drug that doesn't have it's own page yet. OK. Matt 17:44, 24 Dec 2004 (UTC)
    • Ummm, melagatran actually redirects to ximelagatran, because melagatran is only for intravenous use and I don't expect it to be used very often. JFW | T@lk 18:01, 25 Dec 2004 (UTC)
  • alteplase redirects to Tissue plasminogen activator
    • DON'T do this - this article also contains material on physiological function of tPA. If you really feel the urge, you can create an article about rtPA (recombinant tissue plasminogen activator), but I wouldn't. JFW | T@lk 13:57, 22 Dec 2004 (UTC)
  • digitoxin redirects to digitalis
    • The article is on the plant genus with info included on medicinal uses. Matt 16:07, 22 Dec 2004 (UTC)
  • dronabinol redirects to tetrahydrocannabinol
    • I'm sure that people wouldn't agree to it being moved, perhaps if there's more info on the medicinal uses of the substance, then the page can be split.Matt 16:21, 22 Dec 2004 (UTC)
      • I wouldn't mind seeing it moved to dronabinol. People often confuse THC with nabilone, when it is really dronabinol. As long as the first sentence of the lead mentions that dronabinol is THC, then it should avoid confusion. Rad Racer 23:07, 30 Mar 2005 (UTC)
  • enalaprilat redirects to enalapril
    • the article is too short to split at this point, but could be in the future. Matt 16:21, 22 Dec 2004 (UTC)
  • ergotamine, methylergometrine, and pergolide redirect to ergoline
    • each of these should have their own page, when there's enough info to write them. Matt 16:25, 22 Dec 2004 (UTC)
  • filgrastim redirects to granulocyte-colony stimulating factor
    • Same issue that JFW raised with alteplase. Matt 16:32, 22 Dec 2004 (UTC)
  • fosinoprilat redirects to fosinopril
    • The article is too short to split at this point, but could be in the future. Matt 16:36, 22 Dec 2004 (UTC)
  • levonorgestrel redirects to progesterone
    • The article doesn't make it clear why the redirect and I don't know. Seeking further clarification.Matt 18:16, 23 Dec 2004 (UTC)
    • If anything it should probably redirect to progestogen, but would be better off being an actual article Techelf 05:23, 24 Dec 2004 (UTC)
    • levonorgestrel now redirects to progestin which is a more specific and accurate redirect. In the interest of abolishing INN redirects it could be converted into a stub by anyone who wants to do so, but I won't because I have nothing to contribute to such a stub other than the definition that levonorgestrel is a progestin. Col.Kiwi 17:38, 18 Apr 2005 (UTC)
  • Liothyronine redirects to thyroid hormone
    • like alteplase, I think. Matt
      • No, levothyroxine and liothyronine are different thyroid hormone analogues. They all need new pages. Thyroid hormone is about the physiological substance. JFW | T@lk 18:01, 25 Dec 2004 (UTC)
  • Imatinib to imatinib mesylate
    • This suggestion does not make sense to me. The mesylate part of the salt is not related to pharmacological action, it's just one of thousands of possible salts of this compound. Cacycle 18:32, 23 Dec 2004 (UTC)
      • That's a good point, there are several drugs like this. In my list of INNs (from the US gov), this was listed as that particular salt and I don't know why. I just checked the ATC (http://www.whocc.no/atcddd/) and it's just listed as imatinib so I'll change the name in the drug list. I sure wish I had a list of 'official' INNs though. Matt 21:20, 23 Dec 2004 (UTC)
      • If "imatinib mesylate" is the INN, usually "imatinib" is listed as an INN Modified (INNM). Either way, I agree that it would be more appropriate to use the drug name, without the salt. Matt, if you happen to have access to any post-2003(ish) British texts (e.g. Martindale, BNF, British Pharmacopoeia) they'll list the INNs (though sometimes BNF lists INNMs). Techelf 05:23, 24 Dec 2004 (UTC)
  • acitretin redirects to retinoid
    • Retinoids are a class of compounds while acitrecin is one compound belonging to this class. Cacycle 18:59, 23 Dec 2004 (UTC)
  • neoarsphenamine redirects to arsphenamine
    • No info yet to make an article for this drug. Matt 21:54, 23 Dec 2004 (UTC)
  • nicotinamide redirects to niacin
    • which describes both nicotinic acid and nicotinamide. I don't know if the two should have seperate articles or not. Matt 21:59, 23 Dec 2004 (UTC)
  • prednisone redirects to prednisolone
    • prednisone is the prodrug of prednisolone, perhaps someday there'll be enough content to split them. Matt 18:04, 24 Dec 2004 (UTC)
  • pyridoxine redirects to Vitamin B6
    • The page is just a stub and covers several different substances. Matt 18:08, 24 Dec 2004 (UTC)
  • sodium cyclamate redirects to cyclamate
    • Salt issue raised above. Matt 18:27, 24 Dec 2004 (UTC)
  • sulfanilamide redirects to sulfonamide
    • Sulfonamide is the general category that sulfanilamide falls into. Matt 18:34, 24 Dec 2004 (UTC)
  • suramin sodium redirects to suramin
    • Salt issue raised above. Matt 18:36, 24 Dec 2004 (UTC)
  • ubidecarenone redirects to Coenzyme Q
    • seems to be a general category, not clear though. Matt 18:50, 24 Dec 2004 (UTC)
  • betacarotene redirects to carotene
  • ciglitazone redirects to thiazolidinedione
    • general category. Matt 19:22, 24 Dec 2004 (UTC)
    • ciglitazone is not being marketed. JFW | T@lk 18:01, 25 Dec 2004 (UTC)
  • cortisone redirects to corticosteroid
    • general category. Matt 19:25, 24 Dec 2004 (UTC)
  • amfetamine to amphetamine
  • human chorionic gonadotropin to chorionic gonadotropin
    • No, this page is about the physiological hormone, as well as the fertility drug. Split, but do not rename. JFW | T@lk 18:01, 25 Dec 2004 (UTC)
  • Adrenocorticotropic hormone to corticotropin
    • No, this page is about the physiological hormone, as well as synacthen. Split, but do not rename. JFW | T@lk 18:01, 25 Dec 2004 (UTC)
  • Indomethacin to indometacin
  • Folinic acid to calcium folinate
    • Calcium folinate is the salt of Folinic acid. Cacycle 09:13, 31 Mar 2005 (UTC)