WDR3

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WD repeat domain 3
Identifiers
Symbol(s) WDR3; FLJ12796
External IDs OMIM: 604737 MGI: 2443143 HomoloGene: 4937
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10885 269470
Ensembl ENSG00000065183 ENSMUSG00000033285
Uniprot Q9UNX4 n/a
Refseq NM_006784 (mRNA)
NP_006775 (protein)		 NM_175552 (mRNA)
NP_780761 (protein)
Location Chr 1: 118.27 - 118.3 Mb Chr 3: 100.27 - 100.29 Mb
Pubmed search [1] [2]

WD repeat domain 3, also known as WDR3, is a human gene.[1]

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.[1]

[edit] References

  1. ^ a b Entrez Gene: WDR3 WD repeat domain 3.

[edit] Further reading

  • Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220. 
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77-83. doi:10.1038/nature03207. PMID 15635413. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100-9. doi:10.1091/mbc.E02-05-0271. PMID 12429849. 
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1-11. PMID 11790298. 
  • Claudio JO, Liew CC, Ma J, et al. (1999). "Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13.". Genomics 59 (1): 85-9. doi:10.1006/geno.1999.5858. PMID 10395803. 
  • Claudio JO, Liew CC, Dempsey AA, et al. (1999). "Identification of sequence-tagged transcripts differentially expressed within the human hematopoietic hierarchy.". Genomics 50 (1): 44-52. doi:10.1006/geno.1998.5308. PMID 9628821. 
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