WDFY3

From Wikipedia, the free encyclopedia

WD repeat and FYVE domain containing 3

Identifiers

WDFY3; ALFY; KIAA0993; MGC16461; ZFYVE25

External IDs

Gene ontology
Molecular Function:	• beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity • zinc ion binding • metal ion binding
Cellular Component:	• cytoplasm • membrane

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014991 (mRNA)
NP_055806 (protein)

NM_172882 (mRNA)
NP_766470 (protein)

Location

Chr 4: 85.81 - 86.11 Mb

Chr 5: 102.08 - 102.31 Mb

Pubmed search

[1]

[2]

WD repeat and FYVE domain containing 3, also known as WDFY3, is a human gene.^[1]

This gene encodes a protein which contains WD repeats and an FYVE domain. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.^[1]

[edit] References

^ ^a ^b Entrez Gene: WDFY3 WD repeat and FYVE domain containing 3.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107-13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353-8. PMID 9110174.
"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097-108. PMID 9847074.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63-70. PMID 10231032.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Simonsen A, Birkeland HC, Gillooly DJ, et al. (2005). "Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.". J. Cell. Sci. 117 (Pt 18): 4239-51. doi:10.1242/jcs.01287. PMID 15292400.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724-31. doi:10.1038/nature03466. PMID 15815621.