VTI1B

From Wikipedia, the free encyclopedia

Vesicle transport through interaction with t-SNAREs homolog 1B (yeast)

PDB rendering based on 1gl2.

Available structures: 1gl2

Identifiers

Symbol(s)

VTI1B; VTI1; VTI1L; VTI2

External IDs

OMIM: 603207 MGI: 1855688 HomoloGene: 38178

Gene ontology
Cellular Component:	• membrane • integral to membrane
Biological Process:	• intracellular protein transport • vesicle docking during exocytosis • membrane fusion • cell proliferation • vesicle-mediated transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006370 (mRNA)
NP_006361 (protein)

NM_016800 (mRNA)
NP_058080 (protein)

Location

Chr 14: 67.19 - 67.21 Mb

Chr 12: 80.07 - 80.09 Mb

Pubmed search

[1]

[2]

Vesicle transport through interaction with t-SNAREs homolog 1B (yeast), also known as VTI1B, is a human gene.^[1]

[edit] References

^ Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast).

[edit] Further reading

Fischer von Mollard G, Stevens TH (1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.". J. Biol. Chem. 273 (5): 2624–30. PMID 9446565.
Li HC, Tahara H, Tsuyama N, Ide T (1998). "A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts.". Biochem. Biophys. Res. Commun. 247 (1): 70–4. doi:10.1006/bbrc.1998.8737. PMID 9636656.
Subramaniam VN, Loh E, Horstmann H, et al. (2000). "Preferential association of syntaxin 8 with the early endosome.". J. Cell. Sci. 113 ( Pt 6): 997–1008. PMID 10683148.
Antonin W, Holroyd C, Fasshauer D, et al. (2001). "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.". EMBO J. 19 (23): 6453–64. doi:10.1093/emboj/19.23.6453. PMID 11101518.
Wade N, Bryant NJ, Connolly LM, et al. (2001). "Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.". J. Biol. Chem. 276 (23): 19820–7. doi:10.1074/jbc.M010838200. PMID 11278762.
Antonin W, Fasshauer D, Becker S, et al. (2002). "Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.". Nat. Struct. Biol. 9 (2): 107–11. doi:10.1038/nsb746. PMID 11786915.
Kreykenbohm V, Wenzel D, Antonin W, et al. (2003). "The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners.". Eur. J. Cell Biol. 81 (5): 273–80. PMID 12067063.
Antonin W, Dulubova I, Arac D, et al. (2002). "The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly.". J. Biol. Chem. 277 (39): 36449–56. doi:10.1074/jbc.M204369200. PMID 12114520.
Bogdanovic A, Bennett N, Kieffer S, et al. (2002). "Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum.". Biochem. J. 368 (Pt 1): 29–39. doi:10.1042/BJ20020845. PMID 12175335.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Martinez-Arca S, Rudge R, Vacca M, et al. (2003). "A dual mechanism controlling the localization and function of exocytic v-SNAREs.". Proc. Natl. Acad. Sci. U.S.A. 100 (15): 9011–6. doi:10.1073/pnas.1431910100. PMID 12853575.
Yan Q, Sun W, McNew JA, et al. (2004). "Ca2+ and N-ethylmaleimide-sensitive factor differentially regulate disassembly of SNARE complexes on early endosomes.". J. Biol. Chem. 279 (18): 18270–6. doi:10.1074/jbc.M400093200. PMID 14769786.
Hirst J, Miller SE, Taylor MJ, et al. (2005). "EpsinR is an adaptor for the SNARE protein Vti1b.". Mol. Biol. Cell 15 (12): 5593–602. doi:10.1091/mbc.E04-06-0468. PMID 15371541.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.