VS ribozyme

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The Varkud satellite (VS) ribozyme is an RNA enzyme that carries out the cleavage of a phosphodiester bond [1].

[edit] Structure

The VS ribozyme is composed of 5 helices that form an H shape (helices II to VI). The first helix (I) contains the substrate cleavage site in the stem-loop.

[edit] Species Distribution

The VS ribozyme has only been found in DNA of Neurospora mitochondria.

[edit] References

  1. ^ Saville BJ, Collins RA (1990). "A site-specific self-cleavage reaction performed by a novel RNA in Neurospora mitochondria". Cell 61 (4): 685–696. doi:10.1016/0092-8674(90)90480-3. 
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