Vroman effect
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The Vroman effect, named after Leo Vroman, is exhibited by protein adsorption to a surface by blood serum proteins. The highest mobility proteins arrive first and are later replaced by less motile proteins that have a higher affinity for the surface. A typical example of this occurs when fibrin adheres to a biopolymer surface and is later replaced by other proteins. This results in a depletion overall of blood serum levels of fibrinogen.
[edit] References
- Vroman, L. (November 3, 1962). "Effect of Adsorbed Proteins on the Wettability of Hydrophilic and Hydrophobic Solids" (PDF). Nature 196 (196): 476–477. doi:.
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