Talk:Vitamin K

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[edit] Too much vitamin k ???

This is not really a problem. Vitamin K is a cofactor - excess levels do not increase thrombosis risk as such. Only too little (such as in malabsorption of breastfeeding babies) may lead to a coagulopathy. JFW | T@lk 07:53, 5 Nov 2004 (UTC)
Someone who understands the issues might want to add something on the issue of interferance with warfarin . See issues with Anlene milk powder[1]
Better link[2]. This is completely reasonable, although I think using vitamin K for bone health is unproven bunk. JFW | T@lk 14:55, 4 August 2006 (UTC)
Pubmed search. JFW | T@lk 14:57, 4 August 2006 (UTC)

As a patient taking Marcomar (the Swiss equivalent of Warfarin), I suggest being careful about advice in this area. All the doctors I have seen have stressed to NOT CHANGE YOUR NORMAL DIET. They did suggest that eating a large amount (plate full) of cabbage or brussel sprouts wouldn't be clever, but, eating these high % foods shouldn't be a problem in 'normal' portions. The reason for this seems to be the fact that these Anticoagulant drugs act very slowly meaning it is really difficult to establish the correct dose. If you couple the dosage issue with a situation where the patient also changes diet in a significant way, then you have a danger that the blood thins too much or more than expected leading to a danager of bleeding and haemorages. Therefore, my doctors are saying don't change your diet, adjust the drug dose to fit with your normal eating habits. —Preceding unsigned comment added by 128.246.4.6 (talk) 09:41, 15 February 2008 (UTC)

[edit] Why "K"

All the othervitamins go in alphabetical order: A, B, C, D, E, why "Vitamin K"? Why not vitamin F? --Munchkinguy 19:00, 2 Jun 2005 (UTC)

Because the scientist who discovered this antihaemorrhagic vitamin in 1935 was Danish, and called it Koagulation (coagulation) vitamin. JFW | T@lk 22:40, 2 Jun 2005 (UTC)
Also the naming of different B vitamins and other substances had originally been named F,G,H,I e.t.c when they were first discovered but through the years they either adopted another name or have been removed from the vitamin group in general so there are empty positions, the same holds true for "missing" numbers in the B complex. 89.133.150.230 (talk) 20:44, 7 March 2008 (UTC)

[edit] Dangers?

[edit] Physiology of vitamin K

This free article outlines the pleiotropic roles of vitamin K. Worth including. JFW | T@lk 21:22, 6 September 2006 (UTC)

[edit] Slang

I've taken the liberty of revamping the slang section about "vitamin K" as slang for ketamine; the term is in common use and important. The old version stated that ketamine was Schedule I. This is bunk and smacks of poor research at best and fearmongering at worst. I've also decided to remove the term "powerful"-- ketamine may or many not be powerful (whatever a "powerful" drug is), but its potency and efficacy are better addressed in the ketamine article and its references. I also explicitly referred to it as a dissociative anesthetic and linked it as such.

I think the slang section is about as long as it ever needs to be (unless new important usages pop up), since this article should really be about napthoquinones. Is this section a good solution, or should there be a disambiguation page? Kajerm 04:56, 3 November 2006 (UTC)

[edit] Are Vitamin K and ketamine the same thing?

Are vitamin K and ketamine the same thing? I have looked on websites and they tell me they are different however other websites say they are the same. Which is true? —The preceding unsigned comment was added by 88.110.252.29 (talk) 10:39, 10 March 2007 (UTC).

No. This question is addressed in the article at the top in the comment about disambiguation with ketamine. --EricE 18:38, 22 May 2007 (UTC)

[edit] Pictures are inconsistent

The ball and stick pictures do not currently match their respective molecular diagrams. For starters, the diagrams show oxygens double-bonded to carbon, outside the ring. The ball and stick figures show the oxygen as being part of the ring. —Preceding unsigned comment added by 72.227.129.47 (talk) 06:23, 23 January 2008 (UTC)

[edit] Origin of "Vitamin K"

Vitamin K is named K for the Danish, not German, word koagulation (coagulation). This is mentioned in all the biochemistry books (hereunder Stryer: Bochemistry, Voet&Voet, Biochemistry), that deals with vitamin K. Moreover, I am Danish, as the discoverer of vitamin K is, and has heard the story from my biochemistry teachers at different lectures at the university (University of Southern Denmark). Therefore, please do not change the origin of the word back to German again. it is simply not true! PernilleGodiva —Preceding unsigned comment added by PernilleGodiva (talk • contribs) 11:44, 4 February 2008 (UTC)

According to the article: "The new vitamin received the letter K because the initial discoveries were reported in a German journal, in which it was designated as Koagulationsvitamin."
Do you disagree with this statement? --Slashme (talk) 14:28, 4 February 2008 (UTC)
Another reference is Brody, Tom (1999). Nutritional biochemistry. Boston: Academic Press. ISBN 0-12-134836-9.  which says it's from German --Slashme (talk) 14:49, 4 February 2008 (UTC)
And also the Merck Index of Chemicals and Drugs, citing some references:
The designation K is derived from the German "Koagulationsvitamin": Dam, Biochem. Z. 215, 475 (1929); 220, 158 (1930); Nature 135, 652 (1935).
--Slashme (talk) 14:53, 4 February 2008 (UTC)

Fine with me :-)PernilleGodiva (talk) 09:50, 5 February 2008 (UTC)

I will give you, that he published in a German paper. But the vitamin has not been named in German, it just fits snuggly with the spelling being alike on both languages! Therefore, the naming was made in Danish (please look at the alikeness of the words), but published in German, and therefore for the sake of being readable written like that.

It may be that the name was conceived in Danish, but we have to work with published sources. --Slashme (talk) 05:52, 5 February 2008 (UTC)
OK, here's one from the horse's mouth, so to speak. "It is proposed to term this factor vitamin K (Koagulations-Vitamin in German and the Scandinavian languages)." from CLIV. THE ANTIHAEMORRHAGIC VITAMIN OF THE CHICK. BY HENRIK DAM. From the Biochemical Institute, University of Copenhagen. (Received April 8th, 1935.) so maybe we should indeed change the text to read "German and Danish"? --Slashme (talk) 06:00, 5 February 2008 (UTC)

[edit] Sources (of vitamin K)

Just chicken egg yolks? Really? That seems unusually specific. Do we mean all bird eggs or really just chickens? 172.142.84.245 (talk) 04:39, 9 February 2008 (UTC)

I see banana's in the list of main sources, but at 0.5 micrograms per 100 grams, I dispute whether bananas can really be considered a true 'main source' of Vitamin K. I suspect there is a confusion here between the Vitamin K and the mineral Potassium (Chemical symbol K). As a non expert, I have not edited out bananas, but, at least added a link to the banana page that was missing that shows that Vitamin K is not listed as a significant nutrient within the fruit. —Preceding unsigned comment added by 128.246.4.6 (talk) 09:33, 15 February 2008 (UTC)

[edit] topical vitamin k

may be worth having a section in the article on topical use of vitamin k [1] —Preceding unsigned comment added by EBMdoc (talk • contribs) 14:31, 9 February 2008 (UTC)