Vetispiradiene synthase

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In enzymology, a vetispiradiene synthase (EC 4.2.3.21) is an enzyme that catalyzes the chemical reaction

trans,trans-farnesyl diphosphate $\rightleftharpoons$ vetispiradiene + diphosphate

Hence, this enzyme has one substrate, trans,trans-farnesyl diphosphate, and two products, vetispiradiene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming). Other names in common use include vetispiradiene-forming farnesyl pyrophosphate cyclase, pemnaspirodiene synthase, HVS, and vetispiradiene cyclase. This enzyme participates in terpenoid biosynthesis.

[edit] References

IUBMB entry for 4.2.3.21
BRENDA references for 4.2.3.21 (Recommended.)
PubMed references for 4.2.3.21
PubMed Central references for 4.2.3.21
Google Scholar references for 4.2.3.21
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