Talk:Vesicle-associated membrane protein

From Wikipedia, the free encyclopedia

Molecular and Cellular Biology WikiProject This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Stub This article has been rated as stub-Class on the assessment scale.
Low This article is on a subject of low-importance within molecular and cellular biology.

Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

I don't know who created this page, but the pdb model of the synaptobrevin is misleading(!) in sense that what you see is NOT the synaptobrevin that should be a long alpha-helical protein with no beta-strand domains, what is given as monomer is some adaptor protein that binds to synaptobrevin, not synaptobrevin itself. Danko Georgiev MD 02:49, 9 February 2006 (UTC)

You are absolutely correct. I don't how I could have made such an obvious mistake when I made the image. I'll take the image off and add a correct one when I get a chance. Salsb 14:31, 9 February 2006 (UTC)

O.K. I have added correct image of the core SNARE complex. What one can see is the portion of the VAMP-2 that interacts with syntaxin and SNAP-25. Personally I am interested how one can collect in some 3D environment fragments of different pdb files and create a 3D image of cell interior. If someone knows how this can be in principle done, let he/she post his comment, here. Danko Georgiev MD 05:48, 10 February 2006 (UTC)

I have created new more general entry on VAMP, since not all VAMPs are synaptobrevins. The synaptobrevin has its own article. Danko Georgiev MD 11:50, 19 May 2006 (UTC)