VDAC1

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Voltage-dependent anion channel 1
Identifiers
Symbol(s) VDAC1; MGC111064; PORIN; PORIN-31-HL
External IDs OMIM: 604492 MGI: 106919 HomoloGene: 36115
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 7416 22333
Ensembl ENSG00000073905 ENSMUSG00000020402
Uniprot P21796 Q3THL7
Refseq NM_003374 (mRNA)
NP_003365 (protein)		 NM_011694 (mRNA)
NP_035824 (protein)
Location Chr 5: 133.34 - 133.37 Mb Chr 11: 52.2 - 52.23 Mb
Pubmed search [1] [2]

Voltage-dependent anion channel 1, also known as VDAC1, is a human gene.[1]


Contents

[edit] See also

[edit] References

  1. ^ Entrez Gene: VDAC1 voltage-dependent anion channel 1.

[edit] Further reading

  • Verrier F, Mignotte B, Jan G, Brenner C (2004). "Study of PTPC composition during apoptosis for identification of viral protein target.". Ann. N. Y. Acad. Sci. 1010: 126–42. PMID 15033708. 
  • McEnery MW, Snowman AM, Trifiletti RR, Snyder SH (1992). "Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier.". Proc. Natl. Acad. Sci. U.S.A. 89 (8): 3170–4. PMID 1373486. 
  • Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317–20. PMID 1602151. 
  • Jürgens L, Ilsemann P, Kratzin HD, et al. (1991). "Studies on human porin. IV. The primary structures of "Porin 31HM" purified from human skeletal muscle membranes and of "Porin 31HL" derived from human B lymphocyte membranes are identical.". Biol. Chem. Hoppe-Seyler 372 (7): 455–63. PMID 1657034. 
  • Kayser H, Kratzin HD, Thinnes FP, et al. (1990). "[Identification of human porins. II. Characterization and primary structure of a 31-lDa porin from human B lymphocytes (Porin 31HL).]". Biol. Chem. Hoppe-Seyler 370 (12): 1265–78. PMID 2559745. 
  • Blachly-Dyson E, Baldini A, Litt M, et al. (1994). "Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms.". Genomics 20 (1): 62–7. doi:10.1006/geno.1994.1127. PMID 7517385. 
  • Brdiczka D, Kaldis P, Wallimann T (1994). "In vitro complex formation between the octamer of mitochondrial creatine kinase and porin.". J. Biol. Chem. 269 (44): 27640–4. PMID 7525559. 
  • Yu WH, Wolfgang W, Forte M (1995). "Subcellular localization of human voltage-dependent anion channel isoforms.". J. Biol. Chem. 270 (23): 13998–4006. PMID 7539795. 
  • Thomas L, Blachly-Dyson E, Colombini M, Forte M (1993). "Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel.". Proc. Natl. Acad. Sci. U.S.A. 90 (12): 5446–9. PMID 7685903. 
  • Blachly-Dyson E, Zambronicz EB, Yu WH, et al. (1993). "Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.". J. Biol. Chem. 268 (3): 1835–41. PMID 8420959. 
  • Schleiff E, Shore GC, Goping IS (1997). "Human mitochondrial import receptor, Tom20p. Use of glutathione to reveal specific interactions between Tom20-glutathione S-transferase and mitochondrial precursor proteins.". FEBS Lett. 404 (2-3): 314–8. PMID 9119086. 
  • Reymann S, Haase W, Krick W, et al. (1998). "Endosomes: another extra-mitochondrial location of type-1 porin/voltage-dependent anion-selective channels.". Pflugers Arch. 436 (3): 478–80. PMID 9644232. 
  • Narita M, Shimizu S, Ito T, et al. (1999). "Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria.". Proc. Natl. Acad. Sci. U.S.A. 95 (25): 14681–6. PMID 9843949. 
  • Crompton M, Virji S, Ward JM (1999). "Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore.". Eur. J. Biochem. 258 (2): 729–35. PMID 9874241. 
  • Messina A, Oliva M, Rosato C, et al. (1999). "Mapping of the human Voltage-Dependent Anion Channel isoforms 1 and 2 reconsidered.". Biochem. Biophys. Res. Commun. 255 (3): 707–10. doi:10.1006/bbrc.1998.0136. PMID 10049775. 
  • Shimizu S, Narita M, Tsujimoto Y (1999). "Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC.". Nature 399 (6735): 483–7. doi:10.1038/20959. PMID 10365962. 
  • Decker WK, Bowles KR, Schatte EC, et al. (2000). "Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis.". Mamm. Genome 10 (10): 1041–2. PMID 10501981. 
  • Jacotot E, Ravagnan L, Loeffler M, et al. (2000). "The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.". J. Exp. Med. 191 (1): 33–46. PMID 10620603. 
  • Shimizu S, Tsujimoto Y (2000). "Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity.". Proc. Natl. Acad. Sci. U.S.A. 97 (2): 577–82. PMID 10639121. 
  • Stadtmüller U, Eben-Brunnen J, Schmid A, et al. (2000). "Mitochondria-derived and extra-mitochondrial human type-1 porin are identical as revealed by amino acid sequencing and electrophysiological characterisation.". Biol. Chem. 380 (12): 1461–6. PMID 10661876. 

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Membrane transport protein: ion channels
Ca2+: Calcium channel
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.9, 7A) • Navβ (1, 2, 3, 4) • Epithelial sodium channel
K+: Potassium channel
Cl-: Chloride channel
Porin
Cations: TRP
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
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