From Wikipedia, the free encyclopedia
| Vascular endothelial growth factor (VEGF) IRES A |
 |
| Type: |
Cis-reg; IRES; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Published; PubMed |
| Avg length: |
305.5 nucleotides |
| Avg identity: |
92% |
|
This family represents the vascular endothelial growth factor (VEGF) internal ribosome entry site (IRES) A. VEGF is an endothelial cell mitogen with many crucial functions such as embryogenic development and wound healing. The 5' UTR of VEGF mRNA contains two IRES elements which are able to promote efficient translation at the AUG start codon, this family represents IRES A.[1]
[edit] References
- ^ Huez, I; Creancier L, Audigier S, Gensac MC, Prats AC, Prats H (1998). "Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA". Mol Cell Biol 18: 6178–6190. PMID 9774635.
[edit] External links
