Vanillin synthase

From Wikipedia, the free encyclopedia

In enzymology, a vanillin synthase (EC 4.1.2.41) is an enzyme that catalyzes the chemical reaction

3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin + acetyl-CoA

Hence, this enzyme has one substrate, 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA, and two products, vanillin and acetyl-CoA.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming). Other names in common use include 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase, and (acetyl-CoA-forming).

[edit] References

• IUBMB entry for 4.1.2.41
• BRENDA references for 4.1.2.41 (Recommended.)
• PubMed references for 4.1.2.41
• PubMed Central references for 4.1.2.41
• Google Scholar references for 4.1.2.41
• Narbad A, Gasson MJ (Pt 5). "Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens". Microbiology. 144: 1397–405. PMID 9611814. 
• Pometto AL 3rd Crawford DL (1983). "Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus". Appl. Environ. Microbiol. 45: 1582–5. PMID 6870241. 

[edit] External links

The CAS registry number for this enzyme class is 449168-60-9.

• IUBMB entry for 4.1.2.41

• KEGG entry for 4.1.2.41

• BRENDA entry for 4.1.2.41

• NiceZyme view of 4.1.2.41

• EC2PDB: PDB structures for 4.1.2.41

• PRIAM entry for 4.1.2.41

• PUMA2 entry for 4.1.2.41

• IntEnz: Integrated Enzyme entry for 4.1.2.41

• MetaCyc entry for 4.1.2.41

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050547: vanillin synthase

• AMIGO entry for GO code 0050547: vanillin synthase