UXS1
From Wikipedia, the free encyclopedia
UDP-glucuronate decarboxylase 1
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PDB rendering based on 2b69. | ||||||||||||||
Available structures: 2b69 | ||||||||||||||
Identifiers | ||||||||||||||
Symbol(s) | UXS1; UGD; FLJ23591 | |||||||||||||
External IDs | OMIM: 609749 MGI: 1915133 HomoloGene: 41609 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 80146 | 67883 | ||||||||||||
Ensembl | ENSG00000115652 | ENSMUSG00000057363 | ||||||||||||
Uniprot | Q8NBZ7 | Q91XL3 | ||||||||||||
Refseq | NM_025076 (mRNA) NP_079352 (protein) |
NM_026430 (mRNA) NP_080706 (protein) |
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Location | Chr 2: 106.08 - 106.18 Mb | Chr 1: 43.69 - 43.77 Mb | ||||||||||||
Pubmed search | [1] | [2] |
UDP-glucuronate decarboxylase 1, also known as UXS1, is a human gene.[1]
UDP-glucuronate decarboxylase (UGD; EC 4.1.1.35) catalyzes the formation of UDP-xylose from UDP-glucuronate. UDP-xylose is then used to initiate glycosaminoglycan biosynthesis on the core protein of proteoglycans.[supplied by OMIM][1]
[edit] References
[edit] Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
- Moriarity JL, Hurt KJ, Resnick AC, et al. (2002). "UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization.". J. Biol. Chem. 277 (19): 16968–75. doi: . PMID 11877387.
- Hwang HY, Horvitz HR (2002). "The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development.". Proc. Natl. Acad. Sci. U.S.A. 99 (22): 14218–23. doi: . PMID 12391314.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi: . PMID 12975309.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi: . PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi: . PMID 15815621.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi: . PMID 16303743.