UTP-monosaccharide-1-phosphate uridylyltransferase

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In enzymology, an UTP-monosaccharide-1-phosphate uridylyltransferase (EC 2.7.7.64) is an enzyme that catalyzes the chemical reaction

UTP + a monosaccharide 1-phosphate diphosphate + UDP-monosaccharide

Thus, the two substrates of this enzyme are UTP and monosaccharide 1-phosphate, whereas its two products are diphosphate and UDP-monosaccharide.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is '. Other names in common use include UDP-sugar pyrophosphorylase', and PsUSP.

[edit] References

• IUBMB entry for 2.7.7.64
• BRENDA references for 2.7.7.64 (Recommended.)
• PubMed references for 2.7.7.64
• PubMed Central references for 2.7.7.64
• Google Scholar references for 2.7.7.64
• Tsumuraya Y (2004). "UDP-sugar pyrophosphorylase with broad substrate specificity toward various monosaccharide 1-phosphates from pea sprouts". J. Biol. Chem. 279: 45728–36. PMID 15326166. 
• Rudick VL, Weisman RA (1974). "Uridine diphosphate glucose pyrophosphorylase of Acanthamoeba castellanii. Purification, kinetic, and developmental studies". J. Biol. Chem. 249: 7832–40. PMID 4430676. 

[edit] External links

• IUBMB entry for 2.7.7.64

• KEGG entry for 2.7.7.64

• BRENDA entry for 2.7.7.64

• NiceZyme view of 2.7.7.64

• EC2PDB: PDB structures for 2.7.7.64

• PRIAM entry for 2.7.7.64

• PUMA2 entry for 2.7.7.64

• IntEnz: Integrated Enzyme entry for 2.7.7.64

• MetaCyc entry for 2.7.7.64

• Atomic-resolution structures of enzymes belonging to this class