Uridine diphosphate glucose
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Uridine diphosphate glucose | |
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Identifiers | |
CAS number | [133-89-1] |
PubChem | |
MeSH | |
SMILES | C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O) OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O |
Properties | |
Molecular formula | C15H24N2O17P2 |
Molar mass | 566.302 g/mol |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.
Contents |
[edit] Functions
It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases.[1]
It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.
UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.
[edit] Components
UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.
[edit] References
- ^ Rademacher T, Parekh R, Dwek R (1988). "Glycobiology". Annu Rev Biochem 57: 785–838. doi: . PMID 3052290.
[edit] See also
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