Urate-ribonucleotide phosphorylase

From Wikipedia, the free encyclopedia

In enzymology, an urate-ribonucleotide phosphorylase (EC 2.4.2.16) is an enzyme that catalyzes the chemical reaction

urate D-ribonucleotide + phosphate urate + alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are urate D-ribonucleotide and phosphate, whereas its two products are urate and alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is urate-ribonucleotide:phosphate alpha-D-ribosyltransferase. Other names in common use include UAR phosphorylase, and urate-ribonucleotide:phosphate D-ribosyltransferase. This enzyme participates in purine metabolism.

[edit] References

• IUBMB entry for 2.4.2.16
• BRENDA references for 2.4.2.16 (Recommended.)
• PubMed references for 2.4.2.16
• PubMed Central references for 2.4.2.16
• Google Scholar references for 2.4.2.16
• Laster L and Blair A (1963). "An intestinal phosphorylase for uric acid ribonucleoside". J. Biol. Chem. 238: 3348–3357. 

[edit] External links

The CAS registry number for this enzyme class is 9030-29-9.

• IUBMB entry for 2.4.2.16

• KEGG entry for 2.4.2.16

• BRENDA entry for 2.4.2.16

• NiceZyme view of 2.4.2.16

• EC2PDB: PDB structures for 2.4.2.16

• PRIAM entry for 2.4.2.16

• PUMA2 entry for 2.4.2.16

• IntEnz: Integrated Enzyme entry for 2.4.2.16

• MetaCyc entry for 2.4.2.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050384: urate-ribonucleotide phosphorylase

• AMIGO entry for GO code 0050384: urate-ribonucleotide phosphorylase