Uracil-5-carboxylate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, an uracil-5-carboxylate decarboxylase (EC 4.1.1.66) is an enzyme that catalyzes the chemical reaction

uracil 5-carboxylate uracil + CO₂

Hence, this enzyme has one substrate, uracil 5-carboxylate, and two products, uracil and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is uracil-5-carboxylate carboxy-lyase (uracil-forming). Other names in common use include uracil-5-carboxylic acid decarboxylase, and uracil-5-carboxylate carboxy-lyase.

[edit] References

• IUBMB entry for 4.1.1.66
• BRENDA references for 4.1.1.66 (Recommended.)
• PubMed references for 4.1.1.66
• PubMed Central references for 4.1.1.66
• Google Scholar references for 4.1.1.66
• Palmatier RD, McCroskey RP, Abbott MT (1970). "The enzymatic conversion of uracil 5-carboxylic acid to uracil and carbon dioxide". J. Biol. Chem. 245: 6706–10. PMID 5482775. 

[edit] External links

The CAS registry number for this enzyme class is 59299-01-3.

• IUBMB entry for 4.1.1.66

• KEGG entry for 4.1.1.66

• BRENDA entry for 4.1.1.66

• NiceZyme view of 4.1.1.66

• EC2PDB: PDB structures for 4.1.1.66

• PRIAM entry for 4.1.1.66

• PUMA2 entry for 4.1.1.66

• IntEnz: Integrated Enzyme entry for 4.1.1.66

• MetaCyc entry for 4.1.1.66

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050382: uracil-5-carboxylate decarboxylase

• AMIGO entry for GO code 0050382: uracil-5-carboxylate decarboxylase