UQCRC2

From Wikipedia, the free encyclopedia

Ubiquinol-cytochrome c reductase core protein II

Identifiers

External IDs

OMIM: 191329 MGI: 1914253 HomoloGene: 37764

Gene ontology
Molecular Function:	• metalloendopeptidase activity • ubiquinol-cytochrome-c reductase activity • oxidoreductase activity
Cellular Component:	• mitochondrion • mitochondrial respiratory chain • membrane
Biological Process:	• electron transport • oxidative phosphorylation • proteolysis • transport • aerobic respiration

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003366 (mRNA)
NP_003357 (protein)

NM_025899 (mRNA)
NP_080175 (protein)

Location

Chr 16: 21.87 - 21.9 Mb

Chr 7: 120.43 - 120.45 Mb

Pubmed search

[1]

[2]

Ubiquinol-cytochrome c reductase core protein II, also known as UQCRC2, is a human gene.^[1]

[edit] References

^ Entrez Gene: UQCRC2 ubiquinol-cytochrome c reductase core protein II.

[edit] Further reading

Hosokawa Y, Suzuki H, Toda H, et al. (1990). "The primary structure of the precursor to core protein II, a putative member of mitochondrial processing protease family, of rat mitochondrial cytochrome bc1 complex deduced from cDNA sequence analysis.". Biochem. Int. 20 (4): 731-7. PMID 2162168.
Hosokawa Y, Suzuki H, Toda H, et al. (1989). "Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart.". J. Biol. Chem. 264 (23): 13483-8. PMID 2547763.
Duncan AM, Ozawa T, Suzuki H, Rozen R (1994). "Assignment of the gene for the core protein II (UQCRC2) subunit of the mitochondrial cytochrome bc1 complex to human chromosome 16p12.". Genomics 18 (2): 455-6. doi:10.1006/geno.1993.1500. PMID 8288258.
Hu WH, Hausmann ON, Yan MS, et al. (2002). "Identification and characterization of a novel Nogo-interacting mitochondrial protein (NIMP).". J. Neurochem. 81 (1): 36-45. PMID 12067236.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Wen JJ, Garg N (2005). "Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection.". Free Radic. Biol. Med. 37 (12): 2072-81. doi:10.1016/j.freeradbiomed.2004.09.011. PMID 15544925.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.